Detalhe da pesquisa
1.
2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses.
Proc Natl Acad Sci U S A
; 120(42): e2304139120, 2023 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37831739
2.
Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses.
Proc Natl Acad Sci U S A
; 119(36): e2206104119, 2022 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36037386
3.
Ensitrelvir is effective against SARS-CoV-2 3CL protease mutants circulating globally.
Biochem Biophys Res Commun
; 645: 132-136, 2023 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36689809
4.
Efficacy comparison of 3CL protease inhibitors ensitrelvir and nirmatrelvir against SARS-CoV-2 in vitro and in vivo.
J Antimicrob Chemother
; 78(4): 946-952, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36760083
5.
Efficacy of ensitrelvir against SARS-CoV-2 in a delayed-treatment mouse model.
J Antimicrob Chemother
; 77(11): 2984-2991, 2022 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35914182
6.
Discovery of novel cyclic peptide inhibitors of dengue virus NS2B-NS3 protease with antiviral activity.
Bioorg Med Chem Lett
; 27(15): 3586-3590, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28539222
7.
Prophylactic effect of ensitrelvir in mice infected with SARS-CoV-2.
Antiviral Res
; 224: 105852, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38428748
8.
Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in a COVID-19 hamster model.
EBioMedicine
; 99: 104950, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38159532
9.
Pharmacokinetic and Pharmacodynamic Analysis of the 3CL Protease Inhibitor Ensitrelvir in a SARS-CoV-2 Infection Mouse Model.
Viruses
; 15(10)2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37896829
10.
S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.
Sci Transl Med
; 15(679): eabq4064, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36327352
11.
Characterization of the In Vitro and In Vivo Efficacy of Baloxavir Marboxil against H5 Highly Pathogenic Avian Influenza Virus Infection.
Viruses
; 14(1)2022 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35062315
12.
Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19.
J Med Chem
; 65(9): 6499-6512, 2022 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35352927
13.
5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2.
iScience
; 24(10): 103120, 2021 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34541466
14.
Identification of quinolone derivatives as effective anti-Dengue virus agents.
Antiviral Res
; 184: 104969, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33160000
15.
Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil.
Sci Rep
; 9(1): 3466, 2019 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30837531
16.
Single Amino Acid Mutation in Dengue Virus NS4B Protein Has Opposing Effects on Viral Proliferation in Mammalian and Mosquito Cells.
Jpn J Infect Dis
; 71(6): 448-454, 2018 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30068888
17.
Identification of Compound-B, a novel anti-dengue virus agent targeting the non-structural protein 4A.
Antiviral Res
; 155: 60-66, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29758236
18.
Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus.
Virology
; 505: 102-112, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28236746
19.
Generation of recombinant rabies viruses encoding NanoLuc luciferase for antiviral activity assays.
Virus Res
; 215: 121-8, 2016 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26869397
20.
Multiple ETS family proteins regulate PF4 gene expression by binding to the same ETS binding site.
PLoS One
; 6(9): e24837, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21931859